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These instructions, in turn, initiate a myriad of responses, ranging from fostering muscle growth and skin rejuvenation to orchestrating the delicate balance of hormones and body weight

Before IR (8 Gy, 0.6 Gy/min), organoids were treated with CBD (10 M), GW6471 (MedChemExpress, 4 M), GW590735 (MedChemExpress, 1 nM), lipofermata (MedChemExpress, 10 M), 10,12-tricosadiynoic acid (MedChemExpress, 1 M), -linolenic acid (MedChemExpress, 2 M), -linolenic acid (MedChemExpress, 2 M), eicosapentaenoic acid (EPA) (MedChemExpress, 2 M) and cis -9-palmitoleic acid (Sigma-Aldrich, 3 M)

This encapsulation of mitochondria or mitochondrial fragments into EVs forms what are termed mitoEVs [419]

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